Friday, September 7, 2012

Promising New Drug Target For Inflammatory Lung Diseases

The naturally occurring cytokine interleukin-18, or IL-18, plays a key role in inflammation and has been implicated in serious inflammatory diseases for which the prognosis is poor and there are currently limited treatment options. Therapies targeting IL-18 could prove effective against inflammatory diseases of the lung including bronchial asthma and chronic obstructive pulmonary disease (COPD), as described in a review article published in Journal of Interferon & Cytokine Research, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free online at the Journal of Interferon & Cytokine Research website. (http://www.liebertpub.com/jir)

Tomotaka Kawayama and coauthors from Kurume University School of Medicine, Fukuoka, Japan, University of Ryukyus, Okinawa, Japan, and Frederick National Laboratory for Cancer Research, Frederick, MD, review the growing evidence to support the important role IL-18 has in inflammation and how it may help to initiate and worsen inflammatory disorders such as arthritis, dermatitis and inflammatory diseases of the bowel and immune system. In the article "Interleukin-18 in Pulmonary Inflammatory Diseases" (http://online.liebertpub.com/doi/full/10.1089/jir.2012.0029) they describe the potential benefits of therapies aimed at blocking the activity of IL-18 to treat inflammatory lung disease.

"This review provides an interesting and thorough summary of the biology and potential application of IL-18 in the setting of inflammatory pulmonary disease," says Co-Editor-in-Chief Thomas A. Hamilton, PhD, Chairman, Department of Immunology, Cleveland Clinic Foundation.

4 comments:

cme program said...

College of Medicine has the best faculties for cme program internal medecine and they are affiliated with Drexel University College of Medicine, Department of Medicine and have extensive experience for various certification and recertification examinations.

Anonymous said...

Howdy just wanted to give you a quick heads up.

The words in your content seem to be running off the screen in Internet explorer.
I'm not sure if this is a format issue or something to do with internet browser compatibility but I figured I'd post to
let you know. The layout look great though! Hope you get the issue resolved soon.
Cheers
Also visit my web-site ... amazing site

Anonymous said...

I really like your blog.. very nice colors & theme. Did you make this website yourself or did you hire someone to do it for
you? Plz respond as I'm looking to design my own blog and would like to find out where u got this from. thanks
Look into my webpage safe diets

Anonymous said...

A sеnsual massage rendszеr а κoρоnyа the domain Ϲommοnly as a isѕuе оf harm or fгom аn untreated induction itеm іnѕіԁe the
οral сavіty.

Feel free to visit my web page :: web site

Related Posts Plugin for WordPress, Blogger...

Popular Posts